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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12951f9a697950849577fa31c20570ed648c0db7776a0e7d9f37ebd5089f17e9' 
  AND token = 'DBGGZ3JUjkyq4xwhnhW3hRetAOTeIotybfClThsRaC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}