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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf1d312539a88c41b9a5734cd2af59a8106e58320c34b7d36a9928c8319bc68' 
  AND token = 'NvUFyJaQSW1dzdvwUfIlrd29ADfr8i+H/bL9SM/Mq4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}