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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3f37157fb746fd5d17a4f5b347ced21fb4d8e62b32a4bbd074d5fc43de7b56' 
  AND token = 'Gmo6RZtr23QdvFUHZjsrI3NKcDaALYnZie3x9r5KEfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}