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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a4a3e5c5c5ce080b48b4376130fee9845875816a3040eeebcf1220a7a1c186a' 
  AND token = 'd0lLULHpvV9uHZR4IN1HF5MJyKrH0hjYGsTx3Xmgmus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}