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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19d39befd5a115575610bc51f7acdf162a9535ea2ab912639800fcdfe920075' 
  AND token = 'aIym9pdlx9aEfzWoWZ5+SioAsT7r7/rg1f81Ff8KPFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}