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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d7ecdec8492d397108f0036aff40bfa16a1a4cc5093e003e57ee4a4507569c' 
  AND token = 'pDpKLmPHWbt6Q+wikH87kygLmd1BrMym3cssvQVpylQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}