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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581602062f5b9aca301b8e57cca50a6ed188ae0f7fbd168472960e0f8c324b25' 
  AND token = 'ICn2fYNwbEZORR9QxbaLTx6Qe0qyLnBoAA+2Gk3Ij1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}