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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fdefa2e18a91a08a97d398414b72b28943b8b20c199d7a3901e3fae2f90eab3' 
  AND token = 'lZCCW7Aiqgd3yYsujqOQBv3dVZ9fzxyGMhSpcwdx6yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}