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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748c7633eb04dd2981ac59cf43ea98f270578aa7dbd841afca1ecb33fb4725c2' 
  AND token = 'WXN2d0mvXnyP3UdTwLfY1Nns6/bMmLN9IQTzgYSY4o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}