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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b68dc90b9e1125888d66a2a0c1826b3c910a046835e8aaa2579e2412c2c0227' 
  AND token = 'XbjS4r814X3rqmLdCEG4SB3idzlW+tbejSS49a87N8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}