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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd88f1e8b6b0c0956ca5a67646a13f1b93c767e79f259a253b52505257f1e26c9' 
  AND token = '0ZVVC8Pycl2a7UmRrbxQkKZhhQNGzGxd2LImOxGCsAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}