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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153a9b17ee714033134d04fa7e53399c6bbcb080a7dc0f9381173d1c3a1a3424' 
  AND token = 'OvYYR3bmPO5DQWiMU6SbMyCMhVa/0i0S4sJF8JCyAoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}