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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b486722fcfe995f2e1d958a99152f71c0d2938d1151314e813b0b814e75010' 
  AND token = '1KL4VtmG3WZ7DxVlWdh+KIhI8zyoLBiKMeKAf6evjNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}