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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59921695049cc29599c2f1784cd1f9afcf25e00ca639177e8e6fca23b4c47f4c' 
  AND token = 'jaGZE+vo//OXeItAVmsWxhpdtF9ADQzw08ekE48gH8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}