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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21d36459eb68643a745385d71cbf6067d8acb70308be5843bd8ba48f1f2838b' 
  AND token = 'vSTi69qFZ3q4OYzhWEsiWP2yVbft3qBa84nONUiQMDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}