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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53a39d2c7efe4e9102eab0ddb3763c0870a1bbc73356c8278d36e9b37dfdd53' 
  AND token = 'xtZzU+2FD+0oEBkn/S1vqwwgdXhlnQWRDV++nopeeRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}