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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226dd5910b13dc4a0794846bd80856962db9d870fb6de53ab3e19e0bdc61a73c' 
  AND token = 'EmwUlZS90PBrQVx6aXbLmc3ZVyhgZ66C0u/0fi56lo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}