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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0078747e424109d2a85bcc3b917aabefe4a5d03a51986f0b8f3fab6b9636551' 
  AND token = 'rA7/3kUlq9BA1KUf90a1K1jsXc686XS9VOPNUgQ1zTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}