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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64087c0ac3dfb8dbcb0455c8c48d44c6c11149def0e5bbca9ff2ead2c0189bc9' 
  AND token = 'VZHdpx6FRMN//QpmUUJYIult5IpPzWGuhrMXMNMK8Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}