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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b87c9f046b2d7c3b629c6f1e2866cbcd4a15cd79a04d54e7b730e91accef6f' 
  AND token = 'b4E3V0LJQiW5JnOYg3JHKvhdqk5dHe50aRRFS1UfxK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}