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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378f254842b7c5e940d2d0b8ca903ee14de7af601897c49781bf4e7aa2b45f49' 
  AND token = 'yKhlYl68CmGcvG/QUJF8pd44dN5uHcGR6iIok1FcmyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}