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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '172526ba32177e45d4e2149679e1fc39d8e33a0cc5a3ceb7f8016ea043eebda2' 
  AND token = 't6XgbrEM6n4QplUt5KPb/ay5AyeaSTAFJaYTrV2C7yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}