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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2fd760b466d768fa5ef7073620d1abb2291b6101b10ffb0359a851717dd4dad' 
  AND token = 'kxpgf9AFPmGnETcFV3L87AW3MHV0e9qN5ocMkev7EMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}