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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a901ababfd0b1059045a6c176706407a7b929c6e3720d4e2d777bfee4c3e044' 
  AND token = 'nqX3ZcHhfd7CCYBxFd4thC01nL8AXErs4DIBa3Ef3iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}