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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f32f3465e05ba58d22cf52418f58b3730d8ad602ae4f236fc211d4294296759f' 
  AND token = 'nQJ5c2xQD7t7eZ1HMwCfRq+yIMTjr4rWfrG30f3mN9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}