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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '695c221bc59d68e0caf9c9c784248b17c52b67d240cc07e8ed980bfec47c0f5c' 
  AND token = 'Ia3LO4EHF8z1jy4maLxqLwagDGz8bGSsKTY6/S+3Ysk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}