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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f956f7f17d3b651fc24dc82e020b61fca55cff11366475817e1b132b4226c96c' 
  AND token = 'QNMiMk7bxG5Hf62mQN+mifIjVyt5lobu0egvEfVUwuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}