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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da74668c79efd165ebe554d8e67c129bc0506fccb3e4008f8ef443b6eb3702bd' 
  AND token = 'LkEJ39I0e6qQioLPQhkyaOEmkFqOkTIxdCod/VGNs9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}