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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53575c4811a9b81fe60fe7fd123d829e14ff6ad39be40fd54a28d7022509506e' 
  AND token = '3MVZeUtU8h/jB0l4e45gtArKk5elduzZKtugJLfW4n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}