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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16fb35d4a0738b4d84149079c74246ca2b33df65a33a67839371140375770ceb' 
  AND token = 'M63fr38FXe/lpmElI59abqVzHfkMI/37szB7pZnlvVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}