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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e676cefcde07f7129347ea5fd48c4fc17410fc6fde25c55f6401da4cbaac234' 
  AND token = 'HQ18fDydYEj93+X2WNSm+LQ/CA637HNxW22jS7y+WzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}