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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008500e4fb1f7aee0c2d8da1c995a6134bf2fc2b9d643dd13c936ce2714da5e6' 
  AND token = 'yJX6EdZ1zvatECws20Bau1xlsK2ojvzn7DOWeE4CCO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}