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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d374a25a3c8c45baa7e4064b3aee18cd6ac856374c846dc02ec2f211494220' 
  AND token = '1ne7yNUrULtWM1YnuLoj6+FFFh79xp5m9WYkBe/s3tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}