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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d46a1feeb3a03cb0d467f76dc90289d1c9fd33ed4bb805dcd05ae9c76f85e9' 
  AND token = '7bmsDH7QwvNSYGhO2SQgQ9Fi3bO2qhlMo6M34cyik6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}