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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381fd8d9e812b1f9ef6f774b0d13ac11660e95156327b16ab0c2a176f9d444df' 
  AND token = '5BWSszYjNPcbgPIYA93s4XcGSYl65p3EBzWMPCwG3QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}