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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390d5037d1d01134da416ef21e6f7c5dd6563158407b9bfb24330cd8efbf0543' 
  AND token = 'ChAT64mPX8vHAA6gUQzlQW86lRgMm3N3GxbrBzzmuaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}