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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b29287d620e5cda38edcf87b65bcc0681923d8a22731dcdbcb52b91e7a1b51' 
  AND token = 'XlKqG3CIH3bVnYdcrn1v952esPQrAKW0Ip4bvbYPv10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}