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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b82fe89d823d3ca15e92bd182693a3eae4b2b66d49ba7d141952a5cc271ab6a' 
  AND token = 'oJsv+bHXvniUrp3MjAS8+9iiSFZPZe0uUga33DdSyTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}