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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a397662df0c5cee7b1b1106bcfc1a05987b6236d81b298b63e903b66ddb4472' 
  AND token = 'Tmjy4bUplps0n3wx7cyz2TkuadbT5uH10LJBL12FdBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}