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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6b289d2888af6da3e359bb517bad8b65ceb7e8c15d8748767f70b59ecbcb9e5' 
  AND token = 'E4iSzvDcXNemL0EC2fQLWQtbGuKGGmjizznYyB3DpgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}