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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '374296fd00a1c9bee8e25dcc88f621a45f24e051f2ddade9ea2fd32db6c06151' 
  AND token = 'Y/YgpAgJs7w/FKc2T45TZ1yLl8zcLAI8Q1wXx/uHuYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}