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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501b86b58276ac9b2db86ca63ab4dce55f98ce405ed6c3130cedf754d26a0af7' 
  AND token = 'vWem4+o8OhGvCtMYpAYFatYao+KTzcXCSf4dY4PVj40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}