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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4b2370dee5e3dfada8715fb3fc161e373067c70e39ec518fd8c84a8529b354f' 
  AND token = 'iAbLxxH1RfnJsq2gWKFTvfI4Fa+yNvXnifu2PL+vWEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}