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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a509541c8ae15e3cb0da709cbea3bd4cdb21852e3658cf3556b1b761b8bf690b' 
  AND token = 'h9I2HzhSCpqq+vFTOKISFTPbGjYRhfGN1RQGjFqS3RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}