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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073daaef3d39e2d9ee66c8a38f7da3a909c0c2b58430993dc45696830e90e223' 
  AND token = 'Aq2rZBHoO5nk5V2vHlC+JzyAel4482RnHRZ7Exq2slQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}