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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0578e077c8f37c384c77e3882d59574ff6a593af52651159324dc0ed4e70f493' 
  AND token = 'uHocib289yUy6qO2YgQz5P/NG9QRregjI4lQ7f5ksrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}