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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb59c74d2fa459b92c9cb45544ff64921585db57304b6d1999f4ac9205d5429' 
  AND token = 'VYeZuhLivlgqsui+ciQeFk2UX00vImCWHJ68lAZhAaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}