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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11c7aff35724491b47aa201a5f35845681fd31c392fa90a2b3837b219a9ea019' 
  AND token = '5Mm23LIC7BKnRLIiIDRf+GzQsnF9qknjfrDxuDcK4EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}