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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd1291ee23615242173bf81e104f3f99c6a0831234d280d84876afbb2c9083c5' 
  AND token = '2c0gN4f38MAPdFtMl8stSb4Vzs4c8y6sTQZk27j+0Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}