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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146a155be8e002112a91c0073468e5b100d3571e2be05b5c6b443762dd160540' 
  AND token = 'WVVMwiM1VfDqQbCwe00o5LgFyShrZiRaKIJ8eHw9IS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}